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-Structure paper
Title | A potent broad-spectrum protective human monoclonal antibody crosslinking two haemagglutinin monomers of influenza A virus |
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Journal, issue, pages | Nat Commun, Vol. 6, Page 7708-7708, Year 2015 |
Publish date | Sep 3, 2014 (structure data deposition date) |
Authors | Wu, Y. / Cho, M. / Shore, D. / Song, M. / Choi, J. / Jiang, T. / Deng, Y.Q. / Bourgeois, M. / Almli, L. / Yang, H. ...Wu, Y. / Cho, M. / Shore, D. / Song, M. / Choi, J. / Jiang, T. / Deng, Y.Q. / Bourgeois, M. / Almli, L. / Yang, H. / Chen, L.M. / Shi, Y. / Qi, J. / Li, A. / Yi, K.S. / Chang, M. / Bae, J.S. / Lee, H. / Shin, J. / Stevens, J. / Hong, S. / Qin, C.F. / Gao, G.F. / Chang, S.J. / Donis, R.O. |
External links | Nat Commun / PubMed:26196962 |
Methods | X-ray diffraction |
Resolution | 2.795 - 3.5 Å |
Structure data | PDB-4r8w: PDB-4ubd: |
Chemicals | ChemComp-NAG: ChemComp-HOH: |
Source |
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Keywords | IMMUNE SYSTEM / Influenza A Virus / Hemagglutinin / neutralizing antibody / viral protein/immune system / H3N2 / Monoclonal antibody / viral protein-immune system complex |