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TitleCSGID Solves Structures and Identifies Phenotypes for Five Enzymes in Toxoplasma gondii .
Journal, issue, pagesFront Cell Infect Microbiol, Vol. 8, Page 352-352, Year 2018
Publish dateNov 15, 2013 (structure data deposition date)
AuthorsLykins, J.D. / Filippova, E.V. / Halavaty, A.S. / Minasov, G. / Zhou, Y. / Dubrovska, I. / Flores, K.J. / Shuvalova, L.A. / Ruan, J. / El Bissati, K. ...Lykins, J.D. / Filippova, E.V. / Halavaty, A.S. / Minasov, G. / Zhou, Y. / Dubrovska, I. / Flores, K.J. / Shuvalova, L.A. / Ruan, J. / El Bissati, K. / Dovgin, S. / Roberts, C.W. / Woods, S. / Moulton, J.D. / Moulton, H. / McPhillie, M.J. / Muench, S.P. / Fishwick, C.W.G. / Sabini, E. / Shanmugam, D. / Roos, D.S. / McLeod, R. / Anderson, W.F. / Ngo, H.M.
External linksFront Cell Infect Microbiol / PubMed:30345257
MethodsX-ray diffraction
Resolution1.2 - 2.6 Å
Structure data

PDB-4nml:
2.60 Angstrom resolution crystal structure of putative ribose 5-phosphate isomerase from Toxoplasma gondii ME49 in complex with DL-Malic acid
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-4nog:
Crystal structure of a putative ornithine aminotransferase from Toxoplasma gondii ME49 in complex with pyrodoxal-5'-phosphate
Method: X-RAY DIFFRACTION / Resolution: 1.2 Å

PDB-4nu7:
2.05 Angstrom Crystal Structure of Ribulose-phosphate 3-epimerase from Toxoplasma gondii.
Method: X-RAY DIFFRACTION / Resolution: 2.05 Å

PDB-4o0n:
2.4 Angstrom Resolution Crystal Structure of Putative Nucleoside Diphosphate Kinase from Toxoplasma gondii.
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-4odi:
2.6 Angstrom Crystal Structure of Putative Phosphoglycerate Mutase 1 from Toxoplasma gondii
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-5bxi:
1.7 Angstrom Resolution Crystal Structure of Putative Nucleoside Diphosphate Kinase from Toxoplasma gondii with Tyrosine of Tag Bound to Active Site
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-MLT:
D-MALATE

ChemComp-HOH:
WATER

ChemComp-PLP:
PYRIDOXAL-5'-PHOSPHATE

ChemComp-BME:
BETA-MERCAPTOETHANOL

ChemComp-ACT:
ACETATE ION

ChemComp-BTB:
2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-ZN:
Unknown entry

ChemComp-SO4:
SULFATE ION

ChemComp-NA:
Unknown entry

ChemComp-BCT:
BICARBONATE ION / pH buffer*YM

Source
  • toxoplasma gondii (eukaryote)
  • toxoplasma gondii me49 (eukaryote)
KeywordsISOMERASE / Center for Structural Genomics of Infectious Diseases / CSGID / NIAID / National Institute of Allergy and Infectious Diseases / TRANSFERASE / Structural Genomics / ornithine aminotransferase / Toxoplasma / TIM Barrel / ribulose-phosphate 3-epimerase / 2-Layer Sandwich / Putative Nucleoside Diphosphate Kinase / Phosphoglycerate mutase-like

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