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TitleStructure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus.
Journal, issue, pagesScience, Vol. 342, Page 592-598, Year 2013
Publish dateSep 9, 2013 (structure data deposition date)
AuthorsMcLellan, J.S. / Chen, M. / Joyce, M.G. / Sastry, M. / Stewart-Jones, G.B. / Yang, Y. / Zhang, B. / Chen, L. / Srivatsan, S. / Zheng, A. ...McLellan, J.S. / Chen, M. / Joyce, M.G. / Sastry, M. / Stewart-Jones, G.B. / Yang, Y. / Zhang, B. / Chen, L. / Srivatsan, S. / Zheng, A. / Zhou, T. / Graepel, K.W. / Kumar, A. / Moin, S. / Boyington, J.C. / Chuang, G.Y. / Soto, C. / Baxa, U. / Bakker, A.Q. / Spits, H. / Beaumont, T. / Zheng, Z. / Xia, N. / Ko, S.Y. / Todd, J.P. / Rao, S. / Graham, B.S. / Kwong, P.D.
External linksScience / PubMed:24179220
MethodsX-ray diffraction
Resolution2.397 - 3.253 Å
Structure data

PDB-4mmq:
Crystal Structure of Prefusion-stabilized RSV F Variant DS
Method: X-RAY DIFFRACTION / Resolution: 3.253 Å

PDB-4mmr:
Crystal Structure of Prefusion-stabilized RSV F Variant Cav1 at pH 9.5
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

PDB-4mms:
Crystal Structure of Prefusion-stabilized RSV F Variant Cav1 at pH 5.5
Method: X-RAY DIFFRACTION / Resolution: 2.397 Å

PDB-4mmt:
Crystal Structure of Prefusion-stabilized RSV F Variant DS-Cav1 at pH 9.5
Method: X-RAY DIFFRACTION / Resolution: 3.05 Å

PDB-4mmu:
Crystal Structure of Prefusion-stabilized RSV F Variant DS-Cav1 at pH 5.5
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-4mmv:
Crystal Structure of Prefusion-stabilized RSV F Variant DS-Cav1-TriC at pH 9.5
Method: X-RAY DIFFRACTION / Resolution: 2.81 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-PO4:
PHOSPHATE ION

Source
  • human respiratory syncytial virus a2
  • enterobacteria phage t4 (virus)
KeywordsVIRAL PROTEIN / fusion / membrane / structure-based vaccine design

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