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-Structure paper
Title | Structural and thermodynamic basis of the inhibition of Leishmania major farnesyl diphosphate synthase by nitrogen-containing bisphosphonates. |
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Journal, issue, pages | Acta Crystallogr. ,Sect. D, Vol. 70, Page 802-810, Year 2014 |
Publish date | Apr 2, 2013 (structure data deposition date) |
![]() | Aripirala, S. / Gonzalez-Pacanowska, D. / Oldfield, E. / Kaiser, M. / Amzel, L.M. / Gabelli, S.B. |
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Methods | X-ray diffraction |
Resolution | 1.8 - 2.3 Å |
Structure data | ![]() PDB-4jzb: ![]() PDB-4jzx: ![]() PDB-4k10: |
Chemicals | ![]() ChemComp-CA: ![]() ChemComp-IPE: ![]() ChemComp-P2H: ![]() ChemComp-NA: ![]() ChemComp-HOH: ![]() ChemComp-476: ![]() ChemComp-MG: ![]() ChemComp-NI9: ![]() ChemComp-PEG: ![]() ChemComp-ACT: ![]() ChemComp-MES: |
Source |
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![]() | TRANSFERASE/TRANSFERASE INHIBITOR / Geranyl Transferase / FPPS / farnesyl pyrophosphate synthase / farnesyl diphosphate synthase / cytosolic / TRANSFERASE-TRANSFERASE INHIBITOR complex |