+Search query
-Structure paper
Title | Electrophilic fragment-based design of reversible covalent kinase inhibitors. |
---|---|
Journal, issue, pages | J. Am. Chem. Soc., Vol. 135, Page 5298-5301, Year 2013 |
Publish date | Feb 28, 2013 (structure data deposition date) |
Authors | Miller, R.M. / Paavilainen, V.O. / Krishnan, S. / Serafimova, I.M. / Taunton, J. |
External links | J. Am. Chem. Soc. / PubMed:23540679 |
Methods | X-ray diffraction |
Resolution | 2.6 - 3.1002 Å |
Structure data | PDB-4jg6: PDB-4jg7: PDB-4jg8: |
Chemicals | ChemComp-1LB: ChemComp-NA: ChemComp-HOH: ChemComp-1LC: ChemComp-1LE: |
Source |
|
Keywords | TRANSFERASE/TRANSFERASE INHIBITOR / Protein Kinase / Phosphorylation / Covalent Inhibitor / TRANSFERASE-TRANSFERASE INHIBITOR complex |