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-Structure paper
Title | Crystal structure of the ACVR1 kinase domain in complex with the imidazo[1,2-b]pyridazine inhibitor K00135 |
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Journal, issue, pages | To be Published |
Publish date | Feb 29, 2012 (structure data deposition date) |
Authors | Chaikuad, A. / Sanvitale, C. / Cooper, C. / Canning, P. / Mahajan, P. / Daga, N. / Petrie, K. / Alfano, I. / Gileadi, O. / Fedorov, O. ...Chaikuad, A. / Sanvitale, C. / Cooper, C. / Canning, P. / Mahajan, P. / Daga, N. / Petrie, K. / Alfano, I. / Gileadi, O. / Fedorov, O. / Krojer, T. / Filippakopoulos, P. / Muniz, J.R.C. / von Delft, F. / Weigelt, J. / Arrowsmith, C.H. / Edwards, A.M. / Bountra, C. / Bullock, A. / Structural Genomics Consortium (SGC) |
External links | Search PubMed |
Methods | X-ray diffraction |
Resolution | 2.42 Å |
Structure data | PDB-4dym: |
Chemicals | ChemComp-SO4: ChemComp-IYZ: ChemComp-GOL: ChemComp-HOH: |
Source |
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Keywords | TRANSFERASE/TRANSFERASE INHIBITOR / Structural Genomics / Structural Genomics Consortium / SGC / Protein Kinase / TRANSFERASE-TRANSFERASE INHIBITOR complex |