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-Structure paper
Title | Pyridomycin bridges the NADH- and substrate-binding pockets of the enoyl reductase InhA. |
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Journal, issue, pages | Nat. Chem. Biol., Vol. 10, Page 96-98, Year 2014 |
Publish date | Mar 26, 2013 (structure data deposition date) |
Authors | Hartkoorn, R.C. / Pojer, F. / Read, J.A. / Gingell, H. / Neres, J. / Horlacher, O.P. / Altmann, K.H. / Cole, S.T. |
External links | Nat. Chem. Biol. / PubMed:24292073 |
Methods | X-ray diffraction |
Resolution | 1.95 - 2.25 Å |
Structure data | PDB-4bge: PDB-4bgi: PDB-4bii: |
Chemicals | ChemComp-PYW: ChemComp-HOH: ChemComp-I4I: ChemComp-NAD: |
Source |
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Keywords | OXIDOREDUCTASE / TUBERCULOSIS DRUG / ACP ENOYL REDUCTASE |