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-Structure paper
Title | Small-Molecule Inhibitors of the Interaction between the E3 Ligase Vhl and Hif1Alpha |
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Journal, issue, pages | Angew. Chem. Int. Ed. Engl., Vol. 51, Page 11463-, Year 2012 |
Publish date | Aug 31, 2012 (structure data deposition date) |
Authors | Buckley, D.L. / Gustafson, J.L. / Van Molle, I. / Roth, A.G. / Tae, H.S. / Gareiss, P.C. / Jorgensen, W.L. / Ciulli, A. / Crews, C.M. |
External links | Angew. Chem. Int. Ed. Engl. / PubMed:23065727 |
Methods | X-ray diffraction |
Resolution | 2 - 2.8 Å |
Structure data | PDB-4b95: PDB-4b9k: |
Chemicals | ChemComp-ACT: ChemComp-UCK: ChemComp-HOH: ChemComp-TG0: |
Source |
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Keywords | TRANSCRIPTION / HYPOXIA INDUCIBLE FACTOR / HIF-1ALPHA INHIBITOR / LIGASE / INHIBITOR |