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-Structure paper
Title | X-ray structures of progesterone receptor ligand binding domain in its agonist state reveal differing mechanisms for mixed profiles of 11 beta-substituted steroids. |
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Journal, issue, pages | J. Biol. Chem., Vol. 287, Page 20333-20343, Year 2012 |
Publish date | Sep 27, 2011 (structure data deposition date) |
Authors | Lusher, S.J. / Raaijmakers, H.C. / Vu-Pham, D. / Kazemier, B. / Bosch, R. / McGuire, R. / Azevedo, R. / Hamersma, H. / Dechering, K. / Oubrie, A. ...Lusher, S.J. / Raaijmakers, H.C. / Vu-Pham, D. / Kazemier, B. / Bosch, R. / McGuire, R. / Azevedo, R. / Hamersma, H. / Dechering, K. / Oubrie, A. / van Duin, M. / de Vlieg, J. |
External links | J. Biol. Chem. / PubMed:22535964 |
Methods | X-ray diffraction |
Resolution | 1.9 - 2 Å |
Structure data | PDB-4a2j: PDB-4apu: |
Chemicals | ChemComp-AS0: ChemComp-SO4: ChemComp-HOH: ChemComp-OR8: ChemComp-A2K: |
Source |
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Keywords | TRANSCRIPTION / PARTIAL AGONIST / ASOPRISNIL |