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Structure paper

TitleHuman and mouse type I natural killer T cell antigen receptors exhibit different fine specificities for CD1d-antigen complex
Journal, issue, pagesJ. Biol. Chem., Vol. 287, Page 39139-39148, Year 2012
Publish dateAug 24, 2012 (structure data deposition date)
AuthorsWun, K.S. / Ross, F. / Patel, O. / Besra, G.S. / Porcelli, S.A. / Richardson, S.K. / Keshipeddy, S. / Howell, A.R. / Godfrey, D.I. / Rossjohn, J.
External linksJ. Biol. Chem. / PubMed:22995911
MethodsX-ray diffraction
Resolution2.935 - 3.093 Å
Structure data

PDB-3vwj:
Ternary crystal structure of the human NKT TCR-CD1d-C20:2 complex
Method: X-RAY DIFFRACTION / Resolution: 3.093 Å

PDB-3vwk:
Ternary crystal structure of the human NKT TCR-CD1d-4'deoxy-alpha-galactosylceramide complex
Method: X-RAY DIFFRACTION / Resolution: 2.935 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-DB3:
(11Z,14E)-N-[(2S,3S,4R)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]icosa-11,14-dienamide

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-4GH:
N-{(2S,3R)-1-[(4-deoxy-alpha-D-xylo-hexopyranosyl)oxy]-3-hydroxyoctadecan-2-yl}hexacosanamide

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / CD1D / NKT T CELL RECEPTOR / ALPHA-GALACTOSYLCERAMIDE / PROTEIN RECEPTOR COMPLEX / CELL MEMBRANE / DISULFIDE BOND / ENDOSOME / GLYCOPROTEIN / HOST-VIRUS INTERACTION / IMMUNE RESPONSE / IMMUNOGLOBULIN DOMAIN / INNATE IMMUNITY / LYSOSOME / MEMBRANE / TRANSMEMBRANE / DISEASE MUTATION / GLYCATION / MHC I / PYRROLIDONE CARBOXYLIC ACID / SECRETED

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