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Structure paper

TitleMolecular mechanism for inhibition of g protein-coupled receptor kinase 2 by a selective RNA aptamer.
Journal, issue, pagesStructure, Vol. 20, Page 1300-1309, Year 2012
Publish dateDec 7, 2011 (structure data deposition date)
AuthorsTesmer, V.M. / Lennarz, S. / Mayer, G. / Tesmer, J.J.
External linksStructure / PubMed:22727813
MethodsX-ray diffraction
Resolution3.51 - 4.52 Å
Structure data

PDB-3uzs:
Structure of the C13.28 RNA Aptamer Bound to the G Protein-Coupled Receptor Kinase 2-Heterotrimeric G Protein Beta 1 and Gamma 2 Subunit Complex
Method: X-RAY DIFFRACTION / Resolution: 4.52 Å

PDB-3uzt:
Structure of the C13.18 RNA Aptamer in Complex with G Protein-Coupled Receptor Kinase 2
Method: X-RAY DIFFRACTION / Resolution: 3.51 Å

Chemicals

ChemComp-MG:
Unknown entry

Source
  • bos taurus (cattle)
KeywordsTRANSFERASE/RNA / Protein-RNA complex / Protein Kinase Fold / RGS Homology Domain / Pleckstrin Homology Domain / beta propeller / G Protein-Coupled Receptor Phosphorylation / RNA Aptamer / Carboxymethylation / geranylgeranylation / TRANSFERASE-RNA complex

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