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-Structure paper
Title | Importance of ligand bioactive conformation in the discovery of potent indole-diamide inhibitors of the hepatitis C virus NS5B. |
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Journal, issue, pages | J. Am. Chem. Soc., Vol. 132, Page 15204-15212, Year 2010 |
Publish date | May 6, 2010 (structure data deposition date) |
![]() | LaPlante, S.R. / Gillard, J.R. / Jakalian, A. / Aubry, N. / Coulombe, R. / Brochu, C. / Tsantrizos, Y.S. / Poirier, M. / Kukolj, G. / Beaulieu, P.L. |
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Methods | X-ray diffraction |
Resolution | 2.2 - 2.8 Å |
Structure data | ![]() PDB-3mwv: ![]() PDB-3mww: |
Chemicals | ![]() ChemComp-HOH: ![]() ChemComp-SO4: ![]() ChemComp-BIW: |
Source |
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![]() | TRANSFERASE / HCV virus RdRp NS5B polymerase / HCV virus RdRP NS5B polymerase inhibitor |