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-Structure paper
Title | Trapping of palindromic ligands within native transthyretin prevents amyloid formation. |
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Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 107, Page 20483-20488, Year 2010 |
Publish date | Aug 17, 2009 (structure data deposition date) |
![]() | Kolstoe, S.E. / Mangione, P.P. / Bellotti, V. / Taylor, G.W. / Tennent, G.A. / Deroo, S. / Morrison, A.J. / Cobb, A.J. / Coyne, A. / McCammon, M.G. ...Kolstoe, S.E. / Mangione, P.P. / Bellotti, V. / Taylor, G.W. / Tennent, G.A. / Deroo, S. / Morrison, A.J. / Cobb, A.J. / Coyne, A. / McCammon, M.G. / Warner, T.D. / Mitchell, J. / Gill, R. / Smith, M.D. / Ley, S.V. / Robinson, C.V. / Wood, S.P. / Pepys, M.B. |
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Methods | X-ray diffraction |
Resolution | 1.2 - 1.9 Å |
Structure data | ![]() PDB-3ipb: ![]() PDB-3ipe: ![]() PDB-3m1o: |
Chemicals | ![]() ChemComp-JZD: ![]() ChemComp-HOH: ![]() ChemComp-JZE: ![]() ChemComp-CJZ: |
Source |
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![]() | HORMONE / Amyloid / Inhibitor / Palindrome / Amyloidosis / Disease mutation / Gamma-carboxyglutamic acid / Glycoprotein / Neuropathy / Secreted / Thyroid hormone / Transport |