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-Structure paper
Title | Cyclobutanone Analogues of beta-Lactams Revisited: Insights into Conformational Requirements for Inhibition of Serine- and Metallo-beta-Lactamases. |
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Journal, issue, pages | J. Am. Chem. Soc., Vol. 132, Page 2558-2560, Year 2010 |
Publish date | Jan 10, 2010 (structure data deposition date) |
Authors | Johnson, J.W. / Gretes, M. / Goodfellow, V.J. / Marrone, L. / Heynen, M.L. / Strynadka, N.C. / Dmitrienko, G.I. |
External links | J. Am. Chem. Soc. / PubMed:20141132 |
Methods | X-ray diffraction |
Resolution | 2 Å |
Structure data | PDB-3lce: |
Chemicals | ChemComp-GOL: ChemComp-LCE: ChemComp-PO4: ChemComp-HOH: |
Source |
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Keywords | HYDROLASE / beta-lactamase / beta-lactamase inhibitor / beta-lactam mimic / cyclobutanone / hemiketal / Antibiotic resistance / Disulfide bond / Plasmid / Transposable element |