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-Structure paper
Title | Synthesis of glutamic acid analogs as potent inhibitors of leukotriene A4 hydrolase. |
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Journal, issue, pages | Bioorg. Med. Chem., Vol. 16, Page 4963-4983, Year 2008 |
Publish date | Mar 10, 2008 (structure data deposition date) |
Authors | Kirkland, T.A. / Adler, M. / Bauman, J.G. / Chen, M. / Haeggstrom, J.Z. / King, B. / Kochanny, M.J. / Liang, A.M. / Mendoza, L. / Phillips, G.B. ...Kirkland, T.A. / Adler, M. / Bauman, J.G. / Chen, M. / Haeggstrom, J.Z. / King, B. / Kochanny, M.J. / Liang, A.M. / Mendoza, L. / Phillips, G.B. / Thunnissen, M. / Trinh, L. / Whitlow, M. / Ye, B. / Ye, H. / Parkinson, J. / Guilford, W.J. |
External links | Bioorg. Med. Chem. / PubMed:18394906 |
Methods | X-ray diffraction |
Resolution | 1.8 - 2.55 Å |
Structure data | PDB-3cho: PDB-3chp: PDB-3chq: PDB-3chr: PDB-3chs: |
Chemicals | ChemComp-ZN: ChemComp-YB: ChemComp-ACT: ChemComp-4BG: ChemComp-HOH: ChemComp-IMD: ChemComp-4BO: ChemComp-4BQ: ChemComp-4BS: ChemComp-4BU: |
Source |
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Keywords | HYDROLASE / EPOXIDE HYDROLASE / ALPHA-BETA PROTEIN / LEUKOTRIENE BIOSYNTHESIS / METALLOPROTEASE / Inhibitor complex / Alternative splicing / Cytoplasm / Metal-binding / Multifunctional enzyme / Zinc |