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Structure paper

TitleStructural Insights Into the Slit-Robo Complex.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 104, Page 14923-, Year 2007
Publish dateAug 25, 2007 (structure data deposition date)
AuthorsMorlot, C. / Thielens, N.M. / Ravelli, R.B.G. / Hemrika, W. / Romijn, R.A. / Gros, P. / Cusack, S. / Mccarthy, A.A.
External linksProc. Natl. Acad. Sci. USA / PubMed:17848514
MethodsX-ray diffraction
Resolution1.7 - 2.5 Å
Structure data

PDB-2v9q:
First and second Ig domains from human Robo1
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-2v9r:
First and second Ig domains from human Robo1 (Form 2)
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-2v9s:
Second LRR domain of human Slit2
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-2v9t:
Complex between the second LRR domain of Slit2 and The first Ig domain from Robo1
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-HG:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

Source
  • homo sapiens (human)
KeywordsRECEPTOR / PROTO-ONCOGENE / DIFFERENTIATION / PHOSPHORYLATION / DISEASE MUTATION / NEURONAL DEVELOPMENT / IMMUNOGLOBULIN DOMAIN / CHEMOTAXIS / NEUROGENESIS / GLYCOPROTEIN / TRANSMEMBRANE / ROBO1 / MEMBRANE / IG DOMAIN / ROUNDABOUT / DEVELOPMENTAL PROTEIN / STRUCTURAL PROTEIN / EGF-LIKE DOMAIN / STRUCTURAL PROTEIN/RECEPTOR / STRUCTURAL PROTEIN-RECEPTOR COMPLEX / LRR DOMAIN / LEUCINE-RICH REPEAT / SLIT2 / LIGAND / SECRETED / DIFFERENTIATION STRUCTURAL PROTEIN/RECEPTOR / COMPLEX

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