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-Structure paper
Title | Design and Synthesis of HIV-1 Protease Inhibitors Incorporating Oxazolidinones as P2/P2' Ligands in Pseudosymmetric Dipeptide Isosteres. |
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Journal, issue, pages | J. Med. Chem., Vol. 50, Page 4316-4328, Year 2007 |
Publish date | May 31, 2007 (structure data deposition date) |
Authors | Reddy, G.S. / Ali, A. / Nalam, M.N. / Anjum, S.G. / Cao, H. / Nathans, R.S. / Schiffer, C.A. / Rana, T.M. |
External links | J. Med. Chem. / PubMed:17696512 |
Methods | X-ray diffraction |
Resolution | 1.85 - 1.95 Å |
Structure data | PDB-2q54: PDB-2q55: PDB-2q5k: |
Chemicals | ChemComp-PO4: ChemComp-ACT: ChemComp-MU1: ChemComp-HOH: ChemComp-MU0: ChemComp-AB1: |
Source |
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Keywords | HYDROLASE / Drug design / HIV-1 protease / protease inhibitors / protease inhibitor |