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Structure paper

TitleStructures of a Human Papillomavirus (HPV) E6 Polypeptide Bound to MAGUK Proteins: Mechanisms of Targeting Tumor Suppressors by a High-Risk HPV Oncoprotein.
Journal, issue, pagesJ. Virol., Vol. 81, Page 3618-3626, Year 2007
Publish dateAug 9, 2006 (structure data deposition date)
AuthorsZhang, Y. / Dasgupta, J. / Ma, R.Z. / Banks, L. / Thomas, M. / Chen, X.S.
External linksJ. Virol. / PubMed:17267502
MethodsX-ray diffraction
Resolution2.15 - 2.8 Å
Structure data

PDB-2i04:
X-ray crystal structure of MAGI-1 PDZ1 bound to the C-terminal peptide of HPV18 E6
Method: X-RAY DIFFRACTION / Resolution: 2.15 Å

PDB-2i0i:
X-ray crystal structure of Sap97 PDZ3 bound to the C-terminal peptide of HPV18 E6
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-2i0l:
X-ray crystal structure of Sap97 PDZ2 bound to the C-terminal peptide of HPV18 E6.
Method: X-RAY DIFFRACTION / Resolution: 2.31 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • rattus norvegicus (Norway rat)
KeywordsPEPTIDE BINDING PROTEIN / PDZ / E6 binding / tumor suppressor / Sap97 PDZ3 / HPV18 E6 / cervical carcinoma / SAP97 PDZ2 / carcinoma

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