+Search query
-Structure paper
Title | Structural basis for the potent antisickling effect of a novel class of five-membered heterocyclic aldehydic compounds |
---|---|
Journal, issue, pages | J. Med. Chem., Vol. 47, Page 4665-4676, Year 2004 |
Publish date | Sep 5, 2003 (structure data deposition date) |
![]() | Safo, M.K. / Abdulmalik, O. / Danso-Danquah, R. / Burnett, J.C. / Nokuri, S. / Joshi, G.S. / Musayev, F.N. / Asakura, T. / Abraham, D.J. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.85 - 2.25 Å |
Structure data | ![]() PDB-1qxd: ![]() PDB-1qxe: |
Chemicals | ![]() ChemComp-SO4: ![]() ChemComp-HEM: ![]() ChemComp-FU2: ![]() ChemComp-HOH: ![]() ChemComp-OXY: ![]() ChemComp-FUX: |
Source |
|
![]() | OXYGEN STORAGE/TRANSPORT / allosteric; antisickling; relaxed state; hemoglobin; sickle cell; furfural / OXYGEN STORAGE-TRANSPORT COMPLEX / allosteric; antisickling; relaxed state; hemoglobin; sickle cell; 5-hydroxymethyl-2-furfural |