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-Structure paper
Title | Structure of Factor-Inhibiting Hypoxia-Inducible Factor (Hif) Reveals Mechanism of Oxidative Modification of Hif-1Alpha |
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Journal, issue, pages | J. Biol. Chem., Vol. 278, Page 1802-1806, Year 2003 |
Publish date | Aug 12, 2002 (structure data deposition date) |
Authors | Elkins, J.M. / Hewitson, K.S. / McNeill, L.A. / Seibel, J.F. / Schlemminger, I. / Pugh, C. / Ratcliffe, P. / Schofield, C.J. |
External links | J. Biol. Chem. / PubMed:12446723 |
Methods | X-ray diffraction |
Resolution | 2.15 - 2.84 Å |
Structure data | PDB-1h2k: PDB-1h2l: PDB-1h2m: PDB-1h2n: |
Chemicals | ChemComp-FE2: ChemComp-OGA: ChemComp-SO4: ChemComp-HOH: ChemComp-AKG: ChemComp-ZN: |
Source |
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Keywords | TRANSCRIPTION ACTIVATOR/INHIBITOR / TRANSCRIPTION ACTIVATOR-INHIBITOR COMPLEX / FIH / HIF / DSBH / OXYGENASE / TRANSCRIPTION / HYPOXIA / 2- OXOGLUTARATE / ASPARAGINYL HYDROXYLASE / PHOSPHORYLATION / TRANSCRIPTION ACTIVATOR INHIBITOR COMPLEX / HYDROXYLASE / OXIDOREDUCTASE / TRANSCRIPTION ACTIVATOR |