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-Structure paper
Title | Structures of three inhibitor complexes provide insight into the reaction mechanism of the human methylenetetrahydrofolate dehydrogenase/cyclohydrolase. |
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Journal, issue, pages | Biochemistry, Vol. 39, Page 6325-6335, Year 2000 |
Publish date | Nov 29, 1999 (structure data deposition date) |
Authors | Schmidt, A. / Wu, H. / MacKenzie, R.E. / Chen, V.J. / Bewly, J.R. / Ray, J.E. / Toth, J.E. / Cygler, M. |
External links | Biochemistry / PubMed:10828945 |
Methods | X-ray diffraction |
Resolution | 2.2 - 2.7 Å |
Structure data | PDB-1dia: PDB-1dib: PDB-1dig: |
Chemicals | ChemComp-NAP: ChemComp-L24: ChemComp-HOH: ChemComp-L34: ChemComp-L37: ChemComp-ACT: |
Source |
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Keywords | OXIDOREDUCTASE / HYDROLASE / TETRAHYDROFOLATE / DEHYDROGENASE / CYCLOHYDROLASE / NADP / INHIBITOR / ROSSMANN FOLD |