+Search query
-Structure paper
Title | Structure-based design of the first potent and selective inhibitor of human non-pancreatic secretory phospholipase A2. |
---|---|
Journal, issue, pages | Nat. Struct. Biol., Vol. 2, Page 458-465, Year 1995 |
Publish date | Nov 2, 1999 (structure data deposition date) |
Authors | Schevitz, R.W. / Bach, N.J. / Carlson, D.G. / Chirgadze, N.Y. / Clawson, D.K. / Dillard, R.D. / Draheim, S.E. / Hartley, L.W. / Jones, N.D. / Mihelich, E.D. ...Schevitz, R.W. / Bach, N.J. / Carlson, D.G. / Chirgadze, N.Y. / Clawson, D.K. / Dillard, R.D. / Draheim, S.E. / Hartley, L.W. / Jones, N.D. / Mihelich, E.D. / Olkowski, J.L. / Snyder, D.W. / Sommers, C. / Wery, J.-P. |
External links | Nat. Struct. Biol. / PubMed:7664108 |
Methods | X-ray diffraction |
Resolution | 2.2 - 2.8 Å |
Structure data | PDB-1db4: PDB-1db5: PDB-1dcy: |
Chemicals | ChemComp-CA: ChemComp-8IN: ChemComp-HOH: ChemComp-6IN: ChemComp-I3N: |
Source |
|
Keywords | HYDROLASE/HYDROLASE INHIBITOR / S-PLA2 / STRUCTURE-BASED DRUG DESIGN / HYDROLASE-HYDROLASE INHIBITOR complex / S-PLA2; STRUCTURE-BASED DRUG DESIGN |