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-Structure paper
Title | D221 in thymidylate synthase controls conformation change, and thereby opening of the imidazolidine. |
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Journal, issue, pages | Biochemistry, Vol. 37, Page 13893-13901, Year 1998 |
Publish date | Jun 25, 1998 (structure data deposition date) |
Authors | Sage, C.R. / Michelitsch, M.D. / Stout, T.J. / Biermann, D. / Nissen, R. / Finer-Moore, J. / Stroud, R.M. |
External links | Biochemistry / PubMed:9753479 |
Methods | X-ray diffraction |
Resolution | 2.2 - 2.3 Å |
Structure data | PDB-1bjg: PDB-1dna: |
Chemicals | ChemComp-UFP: ChemComp-TMF: ChemComp-HOH: ChemComp-UMP: ChemComp-CB3: |
Source |
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Keywords | TRANSFERASE / ACTIVE SITE MUTANT / REACTION INTERMEDIATE METHYLTRANSFERASE / REACTION INTERMEDIATE / METHYLTRANSFERASE |