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-Structure paper
Title | Propofol rescues voltage-dependent gating of HCN1 channel epilepsy mutants |
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Journal, issue, pages | Nature, Year 2024 |
Publish date | Sep 25, 2023 (structure data deposition date) |
![]() | Kim ED / Wu X / Lee S / Tibbs GR / Cunningham KP / Di Zanni E / Perez ME / Goldstein PA / Accardi A / Larsson HP / Nimigean CM |
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Methods | EM (single particle) |
Resolution | 2.5 - 3.3 Å |
Structure data | EMDB-42116, PDB-8uc7: EMDB-42117, PDB-8uc8: EMDB-44425, PDB-9bc6: EMDB-44426, PDB-9bc7: |
Chemicals | ![]() ChemComp-PFL: ![]() ChemComp-PCW: ![]() ChemComp-CMP: |
Source |
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![]() | TRANSPORT PROTEIN/INHIBITOR / inhibitor / complex / plasma membrane / cyclic nucleotide / TRANSPORT PROTEIN-INHIBITOR complex / TRANSPORT PROTEIN / membrane protein / nanodisc |