Title | Molecular insights into RNA polymerase recycling by mycobacterial HelD |
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Journal, issue, pages | To Be Published |
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Publish date | Aug 4, 2023 (structure data deposition date) |
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Authors | Koval T / Dohnalek L / Libor K / Kouba T |
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External links | Search PubMed |
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Methods | EM (single particle) |
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Resolution | 3.09 - 3.89 Å |
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Structure data | EMDB-18128, PDB-8q3i: Mycobacterium smegmatis RNA polymerase in complex with HelD, SigA and RbpA in State I Method: EM (single particle) / Resolution: 3.11 Å EMDB-18511, PDB-8qn8: Mycobacterium smegmatis RNA polymerase in complex with HelD, SigA and RbpA in State II Method: EM (single particle) / Resolution: 3.14 Å EMDB-18650, PDB-8qti: Mycobacterium smegnatis RNAP open promoter complex with SigmaA and RbpA Method: EM (single particle) / Resolution: 3.09 Å EMDB-18656, PDB-8qu6: Mycobacterium smegnatis RNA polymerase transcription initiation complex with SigmaA, RbpA, HelD and an upstream-fork promoter fragment Method: EM (single particle) / Resolution: 3.45 Å EMDB-18851, PDB-8r2m: Mycobacterium smegnatis RNA polymerase transcription initiation complex with SigmaA, RbpA, HelD N-terminal domain and an upstream-fork promoter fragment; State III conformation Method: EM (single particle) / Resolution: 3.44 Å EMDB-18873, PDB-8r3m: Mycobacterium smegnatis RNA polymerase transcription initiation complex with SigmaA, RbpA, HelD N-terminal, CO and PCh loop domain, and an upstream-fork promoter fragment; State III conformation Method: EM (single particle) / Resolution: 3.49 Å EMDB-18956, PDB-8r6p: Mycobacterium smegnatis RNA polymerase RP2-like transcription initiation complex with SigmaA, RbpA, HelD N-terminal domain and open promoter DNA Method: EM (single particle) / Resolution: 3.16 Å EMDB-18959, PDB-8r6r: Mycobacterium smegnatis RNA polymerase RP2-like transcription initiation complex with SigmaA, RbpA and open promoter DNA Method: EM (single particle) / Resolution: 3.89 Å |
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Chemicals | |
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Source | - mycolicibacterium smegmatis mc2 155 (bacteria)
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Keywords | TRANSCRIPTION / HelD / RNA polymerase / transcription initiation / Mycobacteria / rifampicin resistance |
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