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TitleCrystal structure of dihydrofolate reductase from Yersinia pestis complexed with methotrexate
Journal, issue, pagesTo be Published
Publish dateMay 30, 2014 (structure data deposition date)
AuthorsMaltseva, N. / Kim, Y. / Makowska-Grzyska, M. / Mulligan, R. / Shatsman, S. / Anderson, W.F. / Joachimiak, A.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.297 Å
Structure data

PDB-4qi9:
Crystal structure of dihydrofolate reductase from Yersinia pestis complexed with methotrexate
Method: X-RAY DIFFRACTION / Resolution: 2.297 Å

Chemicals

ChemComp-MTX:
METHOTREXATE / chemotherapy*YM

ChemComp-HOH:
WATER

Source
  • yersinia pestis (bacteria)
KeywordsOXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR / structural genomics / Center for Structural Genomics of Infectious Diseases / CSGID / alpha beta fold / NIAID / National Institute of Allergy and Infectious Diseases / OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex

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