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TitleStructure of human LCK kinase with a small molecule inhibitor
Journal, issue, pagesTo be Published
Publish dateNov 10, 2009 (structure data deposition date)
AuthorsGraves, B.J. / Surgenor, A. / Harris, W. / Smith, I. / Orchard, S. / Flotow, H. / Murray, E.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.8 Å
Structure data

PDB-3kmm:
Structure of human LCK kinase with a small molecule inhibitor
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-LHL:
3-(2,6-dichlorophenyl)-7-({4-[2-(diethylamino)ethoxy]phenyl}amino)-1-methyl-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1H)-one

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE/TRANSFERASE INHIBITOR / TYROSINE KINASE / ATP-binding / Kinase / Nucleotide-binding / Phosphoprotein / Transferase / Tyrosine-protein kinase / TRANSFERASE-TRANSFERASE INHIBITOR complex

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