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Structure paper

TitleCharacterisation of a monoclonal antibody conformationally-selective for native alpha-1-antitrypsin
Journal, issue, pagesTo Be Published
Publish dateJun 27, 2018 (structure data deposition date)
AuthorsElliston, E.L.K. / Miranda, E. / Perez, J. / Jagger, A.M. / Irving, J.A. / Lomas, D.A.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.85 - 2.95 Å
Structure data

PDB-6gxx:
Fab fragment of an antibody selective for alpha-1-antitrypsin in the native conformation
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

PDB-6hx4:
Fab fragment of a native monomer-selective antibody in complex with alpha-1-antitrypsin
Method: X-RAY DIFFRACTION / Resolution: 2.95 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • homo sapiens (human)
KeywordsPROTEIN BINDING / Antibody fragment / Antitrypsin binding / Diagnostic / Monoclonal / conformationally-selective

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