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TitleIntegrative Structural Biology Studies of HIV-1 Reverse Transcriptase Binding to a High-Affinity DNA Aptamer
Journal, issue, pagesCurr Res Struct Biol, Year 2020
Publish dateOct 30, 2017 (structure data deposition date)
AuthorsTuske, S. / Zheng, J. / Olson, E.D. / Ruiz, F.X. / Pascal, B.D. / Bauman, J.D. / Das, K. / DeStefano, J.J. / Musier-Forsyth, K. / Griffin, P.R. / Arnold, E.
External linksCurr Res Struct Biol / Search PubMed
MethodsX-ray diffraction
Resolution2.81 Å
Structure data

PDB-6bhj:
Structure of HIV-1 Reverse Transcriptase Bound to a 38-mer Hairpin Template-Primer RNA-DNA Aptamer
Method: X-RAY DIFFRACTION / Resolution: 2.81 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • human immunodeficiency virus 1
  • synthetic construct (others)
KeywordsTRANSFERASE/DNA / Human immunodeficiency virus 1 / RNA-directed DNA polymerase / Protein/RNA/DNA / Aptamer / TRANSFERASE / TRANSFERASE-DNA complex

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