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Structure paper

TitleStructural basis of the IL-1 receptor TIR domain-mediated IL-1 signaling
Journal, issue, pagesIscience, Vol. 25, Page 104508-, Year 2022
Publish dateJul 14, 2021 (structure data deposition date)
AuthorsZhou, J. / Xiao, Y. / Ren, Y. / Ge, J. / Wang, X.
External linksIscience / Search PubMed
MethodsX-ray diffraction
Resolution1.88 - 3.04 Å
Structure data

PDB-7fcc:
IL-1RAcPb TIR domain
Method: X-RAY DIFFRACTION / Resolution: 2.144 Å

PDB-7fch:
IL-18Rbeta TIR domain
Method: X-RAY DIFFRACTION / Resolution: 1.883 Å

PDB-7fcj:
Zebrafish SIGIRR TIR domain mutant - C299S
Method: X-RAY DIFFRACTION / Resolution: 1.88 Å

PDB-7fcl:
Zebrafish SIGIRR TIR domain
Method: X-RAY DIFFRACTION / Resolution: 3.04 Å

PDB-7fd3:
IL-1RAPL2 TIR domain
Method: X-RAY DIFFRACTION / Resolution: 2.99 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • danio rerio (zebrafish)
KeywordsIMMUNE SYSTEM / IL-1RAcPb / TIR domain / receptor protein / IL-18Rbeta / IL-1 family receptor protein

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