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-Structure paper
Title | Synthetic Antibodies targeting EPHA2 Induce Diverse Signaling-Competent Clusters with Differential Activation |
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Journal, issue, pages | To be Published |
Publish date | Aug 10, 2023 (structure data deposition date) |
Authors | Adams, J.J. / Bruce, H.A. / Ploder, L. / Garcia, J. / Khutoreskaya, G. / Jarvik, N. / Costa, L.E. / Gorelik, M. / Pot, I. / Sicheri, F. ...Adams, J.J. / Bruce, H.A. / Ploder, L. / Garcia, J. / Khutoreskaya, G. / Jarvik, N. / Costa, L.E. / Gorelik, M. / Pot, I. / Sicheri, F. / Blazer, L.L. / Singer, A.U. / Sidhu, S.S. |
External links | Search PubMed |
Methods | X-ray diffraction |
Resolution | 2.6 - 4.6 Å |
Structure data | PDB-8trv: PDB-8tv1: PDB-8tv2: PDB-8tv5: |
Chemicals | ChemComp-IOD: ChemComp-CL: ChemComp-NA: ChemComp-EDO: ChemComp-HOH: ChemComp-MG: |
Source |
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Keywords | SIGNALING PROTEIN/IMMUNE SYSTEM / Cell signalling / antibody / agonist / high affinity / clustering / activation / SIGNALING PROTEIN-IMMUNE SYSTEM complex / SIGNALING PROTEIN / IMMUNE SYSTEM |