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TitleHigh affinity human-derived antibodies effectively rescue moribund mice with lethal severe fever with thrombocytopenia virus infection
Journal, issue, pagesTo Be Published
Publish dateSep 28, 2024 (structure data deposition date)
AuthorsQuan, C.S. / Qi, J.X. / Shi, W.F.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.4 - 3.3 Å
Structure data

PDB-9jqu:
The crystal structure of SFTSV Gn and SD4 antibody complex
Method: X-RAY DIFFRACTION / Resolution: 3.3 Å

PDB-9jqv:
The crystal structure of SFTSV Gn and SD12 antibody complex
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HOH:
WATER

Source
  • sfts virus js4
  • homo sapiens (human)
  • sfts virus hb29
KeywordsVIRAL PROTEIN/IMMUNE SYSTEM / SFTSV / Gn / SD4 / antibody / severe fever with thrombocytopenia syndrome virus / VIRAL PROTEIN-IMMUNE SYSTEM complex / SD12

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