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Structure paper

TitleHuman STK10 bound to GW683134
Journal, issue, pagesTo Be Published
Publish dateSep 19, 2017 (structure data deposition date)
AuthorsSorrell, F.J. / Elkins, J.M.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.43 - 2.56 Å
Structure data

PDB-6eim:
Human STK10 bound to GW683134A
Method: X-RAY DIFFRACTION / Resolution: 1.43 Å

PDB-6i2y:
Human STK10 bound to Foretinib
Method: X-RAY DIFFRACTION / Resolution: 2.56 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-B6E:
~{N}-[5-[4-[[2-fluoranyl-5-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-1~{H}-benzimidazol-2-yl]furan-2-carboxamide

ChemComp-HOH:
WATER

ChemComp-88Z:
N-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / kinase / inhibitor / complex / LOK / foretinib

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