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Structure paper

TitleSingle-domain antibodies directed against hemagglutinin and neuraminidase protect against influenza B viruses
Journal, issue, pagesNat Commun, Vol. 16, Page 5831, Year 2025
Publish dateJun 5, 2024 (structure data deposition date)
AuthorsMatthys A / Felix J / Catani JPP / Roose K / Nerinckx W / Van Buyten B / Fijalkowska D / Callewaert N / Savvides SN / Saelens X
External linksNat Commun / Search PubMed
MethodsEM (single particle)
Resolution2.93 - 3.6 Å
Structure data

50546

9fm1

EMDB-50546, PDB-9fm1:
Cryo-EM structure of Influenza B/Washington/02/2019 virus hemagglutinin in complex with single-domain antibody hVHH-69.
Method: EM (single particle) / Resolution: 2.93 Å

50547

9fm2

EMDB-50547, PDB-9fm2:
Cryo-EM structure of Influenza B/Washington/02/2019 virus neuraminidase in complex with single-domain antibody hVHH-525.
Method: EM (single particle) / Resolution: 3.6 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • influenza b virus
  • lama glama (llama)
KeywordsANTIVIRAL PROTEIN / hemagglutinin / single-domain antibody / complex / neuraminidase

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