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TitleIdentification and non-clinical characterization of SAR444200, a novel anti-GPC3 NANOBODY T cell engager, for the treatment of GPC3+ solid tumors
Journal, issue, pagesTo Be Published
Publish dateApr 12, 2024 (structure data deposition date)
AuthorsMeoni, P. / Vintem, A.P. / Cortez-Retamozo, V. / Jacobs, J. / de Tavernier, E. / Fiorentini, P. / Van Hoorick, D. / Batchelor, J.D. / Svidritskiy, E. / Qiu, Y. ...Meoni, P. / Vintem, A.P. / Cortez-Retamozo, V. / Jacobs, J. / de Tavernier, E. / Fiorentini, P. / Van Hoorick, D. / Batchelor, J.D. / Svidritskiy, E. / Qiu, Y. / Dejonckheere, E. / Li, A. / Pao, L.I. / Buyse, M.A.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.948 Å
Structure data

PDB-9bdo:
Crystal structure of anti-abTCR NANOBODY VHH
Method: X-RAY DIFFRACTION / Resolution: 1.948 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-ACT:
ACETATE ION

ChemComp-HOH:
WATER

Source
  • lama glama (llama)
KeywordsANTITUMOR PROTEIN / NANOBODY / VHH / antibody / TCR

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