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TitleMechanistic insights into the key marine dimethylsulfoniopropionate synthesis enzyme DsyB/DSYB.
Journal, issue, pagesMlife, Year 2022
Publish dateDec 22, 2021 (structure data deposition date)
AuthorsLi, C.Y. / Crack, J.C. / Newton-Payne, S. / Murphy, A.R.J. / Chen, X.L. / Pinchbeck, B.J. / Zhou, S. / Williams, B.T. / Peng, M. / Zhang, X.H. / Chen, Y.
External linksMlife / Search PubMed
MethodsX-ray diffraction
Resolution2.35 - 2.39 Å
Structure data

PDB-7wdq:
DsyB in complex with SAM
Method: X-RAY DIFFRACTION / Resolution: 2.35 Å

PDB-7wdw:
DsyB in complex with SAH and MTHB
Method: X-RAY DIFFRACTION / Resolution: 2.39 Å

Chemicals

ChemComp-SAM:
S-ADENOSYLMETHIONINE

ChemComp-HOH:
WATER

ChemComp-SAH:
S-ADENOSYL-L-HOMOCYSTEINE

ChemComp-H9L:
4-methylsulfanyl-2-oxidanyl-butanoic acid

ChemComp-TRS:
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

Source
  • nisaea denitrificans dsm 18348 (bacteria)
KeywordsTRANSFERASE / Complex / SAM-dependent methyltransferase

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