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TitleMT9, a natural peptide from black mamba venom antagonizes the muscarinic type 2 receptor and reverses the M2R-agonist-induced relaxation in rat and human arteries
Journal, issue, pagesBiomed Pharmacother, Vol. 150, Page 113094-, Year 2022
Publish dateMar 25, 2019 (structure data deposition date)
AuthorsCiolek, J. / Zoukimian, C. / Dhot, J. / Burban, M. / Triquigneaux, M. / Lauzier, B. / Guimbert, C. / Boturyn, D. / Ferron, M. / Ciccone, L. ...Ciolek, J. / Zoukimian, C. / Dhot, J. / Burban, M. / Triquigneaux, M. / Lauzier, B. / Guimbert, C. / Boturyn, D. / Ferron, M. / Ciccone, L. / Tepshi, L. / Stura, E. / Legrand, P. / Robin, P. / Mourier, G. / Schaack, B. / Fellah, I. / Blanchet, G. / Gauthier-Erfanian, C. / Beroud, R. / Servent, D. / De Waard, M. / Gilles, N.
External linksBiomed Pharmacother / Search PubMed
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-6r5m:
Crystal structure of toxin MT9 from mamba venom
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-PGO:
S-1,2-PROPANEDIOL

ChemComp-GOL:
GLYCEROL

ChemComp-ACE:
ACETYL GROUP

ChemComp-HOH:
WATER

Source
  • dendroaspis polylepis (cobra)
KeywordsTOXIN / mamba venom / aminergic toxin

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