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Title | Identification and structure based design of cellularly active cyclo-propyl carboxamide Nicotinamide phosphoribosyltransferase (NAMPT) inhibitors |
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Journal, issue, pages | To Be Published |
Publish date | Aug 28, 2017 (structure data deposition date) |
![]() | Palacios, D. / Meredith, E. / Kawanami, T. / Adams, C. / Chen, X. / Darsigny, V. / Geno, E. / Palermo, M. / Guy, C. / Hewett, J. ...Palacios, D. / Meredith, E. / Kawanami, T. / Adams, C. / Chen, X. / Darsigny, V. / Geno, E. / Palermo, M. / Guy, C. / Hewett, J. / Tierney, L. / THigale, S. / Weihofen, W.A. / Agrikar, U. / Boynton, G. / George, E. / Wang, L. |
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Methods | X-ray diffraction |
Resolution | 2.44 - 2.53 Å |
Structure data | ![]() PDB-6atb: ![]() PDB-6azj: ![]() PDB-6b75: ![]() PDB-6b76: |
Chemicals | ![]() ChemComp-BWA: ![]() ChemComp-GOL: ![]() ChemComp-PO4: ![]() ChemComp-DMS: ![]() ChemComp-HOH: ![]() ChemComp-C5V: ![]() ChemComp-CVP: ![]() ChemComp-CVJ: |
Source |
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![]() | TRANSFERASE / Complex |