EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Discovery and Exploration of Protein Kinase CK2 Binding Sites Using CK2alpha Cys336Ser as an Exquisite Crystallographic Tool
ジャーナル・号・ページ	Kinases Phosphatases, Year 2023
掲載日	2023年8月15日 (構造データの登録日)
著者	Werner, C. / Lindenblatt, D. / Viht, K. / Uri, A. / Niefind, K.
リンク	Kinases Phosphatases / PubMedで検索
手法	X線回折
解像度	1.03 - 1.352 Å
構造データ	PDB-8q77: STRUCTURE OF PROTEIN KINASE CK2 CATALYTIC SUBUNIT (ISOFORM CK2ALPHA'; CSNK2A2 GENE PRODUCT) IN COMPLEX WITH THE BISUBSTRATE INHIBITOR ARC-780 手法: X-RAY DIFFRACTION / 解像度: 1.255 Å PDB-8q9s: STRUCTURE OF PROTEIN KINASE CK2 CATALYTIC SUBUNIT (ISOFORM CK2ALPHA'; CSNK2A2 GENE PRODUCT) IN COMPLEX WITH THE INHIBITOR SGC-CK2-1 手法: X-RAY DIFFRACTION / 解像度: 1.352 Å PDB-8qbu: STRUCTURE OF PROTEIN KINASE CK2 CATALYTIC SUBUNIT (ISOFORM CK2ALPHA'; CSNK2A2 GENE PRODUCT) IN COMPLEX WITH THE INHIBITOR CX-4945 AND THE ALPHA-D-POCKET LIGAND 3,4-DICHLORO PHENETHYLAMINE (DPA) 手法: X-RAY DIFFRACTION / 解像度: 1.09 Å PDB-8qcd: STRUCTURE OF PROTEIN KINASE CK2 CATALYTIC SUBUNIT (ISOFORM CK2ALPHA'; CSNK2A2 GENE PRODUCT) IN COMPLEX WITH THE INHIBITOR 4,5,6,7-TETRABROMOBENZOTRIAZOLE 手法: X-RAY DIFFRACTION / 解像度: 1.03 Å PDB-8qcg: STRUCTURE OF THE CATALYTIC SUBUNIT OF PROTEIN KINASE CK2 (CK2ALPHA') IN COMPLEX WITH THE NON-HYDROLYZABLE ATP ANALOGUE AMPPNP 手法: X-RAY DIFFRACTION / 解像度: 1.04 Å PDB-8qf1: STRUCTURE OF THE CATALYTIC SUBUNIT OF PROTEIN KINASE CK2 (CK2ALPHA') IN COMPLEX WITH THE NON-HYDROLYZABLE GTP ANALOGUE GMPPNP 手法: X-RAY DIFFRACTION / 解像度: 1.32 Å
化合物	ChemComp-LN3: (2~{S})-2-[[(2~{S})-2-[[(2~{S})-2-[12-[[4-[[5-(4-carboxyphenyl)-1,3-thiazol-2-yl]amino]-4-oxidanylidene-butanoyl]-(2-hydroxy-2-oxoethyl)amino]dodecanoylamino]-4-oxidanyl-4-oxidanylidene-butanoyl]amino]-4-oxidanyl-4-oxidanylidene-butanoyl]amino]butanedioic acid ChemComp-EDO: 1,2-ETHANEDIOL / エチレングリコ-ル ChemComp-CL: Unknown entry / クロリド ChemComp-HOH: WATER ChemComp-QBE: ~{N}-[5-[[3-cyano-7-(cyclopropylamino)-3~{H}-pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-methyl-phenyl]propanamide ChemComp-42J: 2-(3,4-dichlorophenyl)ethanamine / 3,4-ジクロロフェネチルアミン ChemComp-3NG: 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid / CX-4945 / 化学療法薬, 阻害剤YM ChemComp-TBS: 4,5,6,7-TETRABROMOBENZOTRIAZOLE / 4,5,6,7-テトラブロモ-1H-ベンゾトリアゾ-ル ChemComp-ANP: PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER / AMP-PNP / AMP-PNP, エネルギー貯蔵分子類似体YM ChemComp-MG: Unknown entry / マグネシウムジカチオン ChemComp-GNP: PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER / Gpp(NH)p / GppNHp, GMPPNP, エネルギー貯蔵分子類似体*YM
由来	homo sapiens (ヒト)
キーワード	TRANSFERASE / protein kinase CK2 casein kinase 2 bisubstrate inhibitor N-terminal segment ligand binding site / protein kinase CK2 casein kinase 2 inhibitor SGC-CK2-1 / protein kinase CK2 casein kinase 2 inhibitor TBB