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TitleComputational-Aided Rational Mutation Design of Pertuzumab to Overcome Active HER2 Mutation S310F through Antibody-Drug Conjugates
Journal, issue, pagesTo Be Published
Publish dateDec 15, 2024 (structure data deposition date)
AuthorsBai X / Xu L / Wang Z / Zhuang X / Ning J / Sun Y / Wang H / Guo Y / Xu Y / Guo J ...Bai X / Xu L / Wang Z / Zhuang X / Ning J / Sun Y / Wang H / Guo Y / Xu Y / Guo J / Chen S / Pan L
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.0 Å
Structure data

62753

9l1s

EMDB-62753, PDB-9l1s:
Structure of the HER2 (S310F) - pertuzumab (T30S/D31A) complex
Method: EM (single particle) / Resolution: 3.0 Å

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / antigen / antibody

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