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TitleCrystal structure of dihydroorotate dehydrogenase from Leishmania brasiliensis in complex with 5-benzylidenepyrimidine-2,4,6(1H,3H,5H)-trione
Journal, issue, pagesTo Be Published
Publish dateJun 18, 2024 (structure data deposition date)
AuthorsFroes, T.Q. / Vaidergorn, M.M. / dos Santos, T. / Leite, P.I.P.L. / Godoi, B.F. / Emery, F.S. / Nonato, M.C.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.75 Å
Structure data

PDB-9cb8:
Crystal structure of dihydroorotate dehydrogenase from Leishmania brasiliensis in complex with 5-benzylidenepyrimidine-2,4,6(1H,3H,5H)-trione
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

Chemicals

ChemComp-FMN:
FLAVIN MONONUCLEOTIDE

ChemComp-GOL:
GLYCEROL

PDB-1avs:
X-RAY CRYSTALLOGRAPHIC STUDY OF CALCIUM-SATURATED N-TERMINAL DOMAIN OF TROPONIN C

ChemComp-HOH:
WATER

Source
  • leishmania braziliensis (eukaryote)
KeywordsOXIDOREDUCTASE / LbDHODH / covalent / inhibitor / orotate

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