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TitleTwelve phosphomimetic mutations induce the assembly of recombinant full-length human tau into paired helical filaments
Journal, issue, pagesTo Be Published
Publish dateOct 22, 2024 (structure data deposition date)
AuthorsLovestam S / Scheres SHW / Goedert M
External linksSearch PubMed
MethodsEM (helical sym.)
Resolution2.48 - 2.72 Å
Structure data

51884

9h5g

EMDB-51884, PDB-9h5g:
PAD12 0N3R:0N4R tau PHF
Method: EM (helical sym.) / Resolution: 2.48 Å

51886

9h5j

EMDB-51886, PDB-9h5j:
PAD12 0N3R tau PHF seeded by AD
Method: EM (helical sym.) / Resolution: 2.72 Å

Source
  • homo sapiens (human)
KeywordsPROTEIN FIBRIL / Amyloid / alzheimer

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