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TitleCrystal Structure Analysis of full-length Bcl-XL in complex with the inhibitor ABT-263
Journal, issue, pagesTO BE PUBLISHED
Publish dateJun 18, 2014 (structure data deposition date)
AuthorsKorste, A. / Vetter, I.R. / Stoll, R.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.3 Å
Structure data

PDB-4qnq:
Crystal Structure Analysis of full-length Bcl-XL in complex with the inhibitor ABT-263
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-1XJ:
4-(4-{[2-(4-chlorophenyl)-5,5-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-N-[(4-{[(2R)-4-(morpholin-4-yl)-1-(phenylsulfanyl)butan-2-yl]amino}-3-[(trifluoromethyl)sulfonyl]phenyl)sulfonyl]benzamide / anticancer, inhibitor*YM

ChemComp-HOH:
WATER

Source
  • rattus norvegicus (Norway rat)
KeywordsAPOPTOSIS/APOPTOSIS inhibitor / ALPHA-HELICAL PROTEIN / APOPTOSIS / APOPTOSIS-APOPTOSIS inhibitor complex

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