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Structure paper

TitleCrystal Structure, Stability and siRNA Activity of Phosphorodithioate-Modified RNAs
Journal, issue, pagesTo be Published
Publish dateSep 13, 2014 (structure data deposition date)
AuthorsPallan, P.S. / Yang, X. / Sierant, M. / Abeydeera, N.D. / Hassell, T. / Martinez, C. / Janicka, M. / Nawrot, B. / Egli, M.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.13 - 1.19 Å
Structure data

PDB-4rby:
First X-ray structure of RNA containing guanosine phosphorodithioate
Method: X-RAY DIFFRACTION / Resolution: 1.19 Å

PDB-4rbz:
X-ray structure of RNA containing adenosine phosphorodithioate
Method: X-RAY DIFFRACTION / Resolution: 1.18 Å

PDB-4rc0:
X-ray structure of RNA containing guanosine phosphorodithioate
Method: X-RAY DIFFRACTION / Resolution: 1.13 Å

Chemicals

ChemComp-SR:
STRONTIUM ION

ChemComp-HOH:
WATER

Source
  • synthetic construct (others)
KeywordsRNA / phosphorodithioate RNA / guanosine phosphorodithioate / phosphorothioate / guanosine analogue / hydrophobic / backbone / adenosine phosphorodithioate / adenosine analogue

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