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Structure paper

Title(+)ML-SI3 bound TRPML2 in an open state
Journal, issue, pagesTo Be Published
Publish dateDec 3, 2024 (structure data deposition date)
AuthorsSchmiege P / Li X
External linksSearch PubMed
MethodsEM (single particle)
Resolution2.61 Å
Structure data

48142

9ekz

EMDB-48142, PDB-9ekz:
(+)ML-SI3 bound TRPML2 in an open state
Method: EM (single particle) / Resolution: 2.61 Å

Chemicals

ChemComp-ZB4:
N-{(1S,2S)-2-[4-(2-methoxyphenyl)piperazin-1-yl]cyclohexyl}benzenesulfonamide / channel blocker, antagonist*YM

Source
  • homo sapiens (human)
KeywordsMEMBRANE PROTEIN / TRPML / calcium channel / ion transport

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