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TitleDistinct Classes of HIV-1 Cross-Clade Neutralizing Antibodies Targeting Fusion Peptide Elicited in Mice by Diverse Immunization Regimens
Journal, issue, pagesTo Be Published
Publish dateMay 29, 2020 (structure data deposition date)
AuthorsXu, K. / Kwong, P.D.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.7 - 2.359 Å
Structure data

PDB-6x78:
Vaccine-elicited mouse FP-targeting neutralizing antibody vFP48.03 in complex with HIV fusion peptide (residue 512-519)
Method: X-RAY DIFFRACTION / Resolution: 2.359 Å

PDB-6x7w:
Vaccine-elicited mouse FP-targeting neutralizing antibody vFP49.02 in complex with HIV fusion peptide (residue 512-519)
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • human immunodeficiency virus 1
KeywordsIMMUNE SYSTEM/VIRAL PROTEIN / HIV / fusion peptide / antibody / IMMUNE SYSTEM-VIRAL PROTEIN complex

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