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-Structure paper
Title | Fragment screening using biolayer interferometry reveals ligands targeting the SHP-motif binding site of the AAA+ ATPase p97 |
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Journal, issue, pages | Commun Chem, Vol. 5, Page 169-, Year 2022 |
Publish date | Oct 1, 2021 (structure data deposition date) |
![]() | Bothe, S. / Hanzelmann, P. / Bohler, S. / Kehrein, J. / Zehe, M. / Wiedemann, C. / Hellmich, U.A. / Brenk, R. / Schindelin, H. / Sotriffer, C. |
![]() | ![]() |
Methods | X-ray diffraction |
Resolution | 1.73 Å |
Structure data | ![]() PDB-7pux: |
Chemicals | ![]() ChemComp-ADP: ![]() ChemComp-FMT: ![]() ChemComp-6LY: ![]() ChemComp-PEG: ![]() ChemComp-NA: ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE / p97 / VCP / fragment screening |