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TitleBiochemical and structural insights of multifunctional flavin-dependent monooxygenase FlsO1-catalyzed unexpected xanthone formation
Journal, issue, pagesNat Commun, Vol. 13, Page 5386-, Year 2022
Publish dateNov 11, 2021 (structure data deposition date)
AuthorsYang, C. / Zhang, L. / Zhang, W. / Huang, C. / Zhu, Y. / Jiang, X. / Liu, W. / Zhao, M. / De, B.C. / Zhang, C.
External linksNat Commun / Search PubMed
MethodsX-ray diffraction
Resolution2.3 Å
Structure data

PDB-7vwp:
Structure of the flavin-dependent monooxygenase FlsO1 from the biosynthesis of fluostatinsin
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-PO4:
PHOSPHATE ION

ChemComp-FAD:
FLAVIN-ADENINE DINUCLEOTIDE / FAD*YM

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • micromonospora rosaria (bacteria)
KeywordsOXIDOREDUCTASE / hydroxylation / benzo[b]-fluorene / epoxidation / Baeyer-Villiger Oxidation / prejadomycin

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