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TitleB cell and antibody targeting of transplant alloantigen epitopes is supported by both self and allo-recognition
Journal, issue, pagesTo Be Published
Publish dateJun 21, 2023 (structure data deposition date)
AuthorsKillian Jr, J.T. / King, R.G. / Kizziah, J.L. / Fucile, C.F. / Diaz-Avalos, R. / Qiu, S. / Silva-Sanchez, A. / Mousseau, B.J. / Macon, K.J. / Callahan, A.R. ...Killian Jr, J.T. / King, R.G. / Kizziah, J.L. / Fucile, C.F. / Diaz-Avalos, R. / Qiu, S. / Silva-Sanchez, A. / Mousseau, B.J. / Macon, K.J. / Callahan, A.R. / Yang, G. / Hossain, E.M. / Akther, J. / Good, D.B. / Kelso, S. / Houp, J.A. / Rosenblum, F. / Porrett, P.M. / Ong, S.C. / Kumar, V. / Ollmann Saphire, E. / Kearney, J.F. / Randall, T.D. / Rosenberg, A.F. / Green, T.J. / Lund, F.E.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution3.84 Å
Structure data

PDB-8t7r:
Crystal structure of human leukocyte antigen A*0101 in complex with the Fab of alloreactive antibody E07
Method: X-RAY DIFFRACTION / Resolution: 3.84 Å

Source
  • homo sapiens (human)
  • cytomegalovirus
KeywordsIMMUNE SYSTEM / human leukocyte antigen / HLA / HLA class I / antibodies / autoimmunity / Fab / alloreactive

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