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TitleCrystal structure of human methionine adenosyltransferase 2A (MAT2A) in complex with S-adenosylmethionine, adenosin and diphosphono-aminophosphonic acid.
Journal, issue, pagesTo Be Published
Publish dateSep 1, 2022 (structure data deposition date)
AuthorsNawrotek, A. / Vuillard, L. / Miallau, L.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.154 Å
Structure data

PDB-8axz:
Crystal structure of human methionine adenosyltransferase 2A (MAT2A) in complex with S-adenosylmethionine, adenosin and diphosphono-aminophosphonic acid.
Method: X-RAY DIFFRACTION / Resolution: 1.154 Å

Chemicals

ChemComp-PPK:
(DIPHOSPHONO)AMINOPHOSPHONIC ACID

ChemComp-MG:
Unknown entry

ChemComp-K:
Unknown entry

ChemComp-SAM:
S-ADENOSYLMETHIONINE

ChemComp-ADN:
ADENOSINE

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / methionine adenosyltransferase / SAM-producing metabolic enzyme / cancer target

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